Urease, a nickel-dependent metalloenzyme produced by diverse pathogens, catalyses the hydrolysis of urea into ammonia and carbon dioxide, a reaction central to microbial survival in hostile ...
Urea transporter (UT) inhibitors are a promising class of diuretics, as selective inhibitors targeting UT-A subtypes have demonstrated considerable therapeutic potential. Herein, we employ a two-round ...
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